Iran says US support for Israeli attacks rendered nuclear talks meaningless

Iranian air defenses in Isfahan are attempting to shoot down Israeli projectiles amid a new wave of airstrikes hitting several parts of Iran, including Tehran.

Multiple explosions hit areas in Hakimiyeh and Tehranpars neighborhoods in eastern Tehran, according to videos obtained by Iran International.

International Atomic Energy Agency chief Raphael Grossi told the United Nations on Friday that an Israeli attack on Iran's Natanz nuclear facility destroyed an area where highly enriched uranium was produced.

"Above ground, part of the pilot fuel enrichment plant where Iran was producing uranium enriched up to 60% uranium-235 has been destroyed," Grossi said.

"Electricity infrastructure at the facility, an electrical substation, main electric power supply building, emergency power supply and backup generators have also been destroyed."

"There is no indication of a physical attack on the underground cascade hall containing part of the pilot fuel enrichment plant and the main fuel enrichment plant. However, the loss of power to the cascade may have damaged the centrifuges there."

Iran’s armed forces are fully prepared for all scenarios and that the recent response to Israel was only a small part of the country’s capabilities, Revolutionary Guards commander Ahmad Vahidi told the state TV Friday night.

Iran’s attack on Israel, code named the True Promise 3 operation, will continue for as long as necessary, Vahidi added.

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"We unequivocally and forcefully condemn Israeli unlawful and terrorist military aggression against Iran," Iran's Ambassador to the United Nations Amir-Saeid Iravani said on Friday.

"Israel, the most loudest and violent regime in the world, committed these barbaric attacks with the full intelligence, operational and political backing of the United States government," he added.

“So far, 78 people, including senior military officials, have been martyred and over 320 other injured. The overwhelming majority of them (are) civilians, including women and children."

Iravani called for other countries to condemn Israel's campaign.

"This aggression constitutes a declaration of war ... Israel attacked Iran. Israel violated international law. Israel must be held accountable."

Israeli Prime Minister Benjamin Netanyahu said in a video message addressed to the Iranian people on Friday that his country's attacks could pave the way for them to overthrow the Islamic Republic.

"The objective of Israel's military operation is to remove this threat, both the nuclear threat and the ballistic missile threat to Israel. And as we achieve our objectives, we're also clearing the path for you to achieve your objective, which is freedom."

"The time has come for you to unite around your flag and your historic legacy by standing up for your freedom from an evil and oppressive regime. "

"(Tehran) has never been weaker. This is your opportunity to stand up and let your voices be heard," Netanyahu added.

"Our fight is with our common enemy, a murderous regime that both oppresses you and impoverishes you brave people of Iran, your light will defeat the darkness. I'm with you. The people of Israel are with you."