Uranium enrichment is non-negotiable, senior Iranian lawmaker says

Iran’s Armed Forces General Staff warned on Friday that any US action in the region could lead to what it described as consequences similar to America’s past military engagements in Vietnam and Afghanistan.

“Any US mischief in the region will bring a fate like Vietnam and Afghanistan,” state media quoted the military as saying in a statement marking the anniversary of the 1982 liberation of Khorramshahr, a strategic city recaptured from Iraqi forces during the Iran-Iraq war.

The statement accused Washington of stirring regional tensions and using what it called “Iranophobia” to extract wealth from Arab states, while asserting that Iran’s approach to the region remains focused on stability and sovereignty.

Iran’s Deputy Foreign Minister Majid Takht-Ravanchi said Tehran would not accept any deal that denies its right to enrich uranium, accusing the United States of shifting positions and undermining talks.

“The Americans must decide: do they want a deal or confrontation? They can’t have both,” Takht-Ravanchi told Der Spiegel in an interview published Friday.

He said US envoy Steve Witkoff initially floated a compromise on 3.67% enrichment but later insisted on zero enrichment, which Takht-Ravanchi called unacceptable and outside the scope of negotiations.

“We cannot rely on foreign fuel supplies. Past experience shows we must be self-sufficient,” he said.

Takht-Ravanchi defended Iran’s higher-level enrichment as peaceful and necessary for research and medicine. “There are uses for 60% enrichment in scientific and medical fields. As long as it’s peaceful, there is no issue.”

Iranian Foreign Minister Abbas Araghchi arrived in Rome on Friday ahead of the fifth round of indirect talks with the United States, Iranian state media reported.

The talks are scheduled to begin at 3 p.m. Iran time (1:30 p.m. local time in Itay), according to the report.

A senior Iranian lawmaker said on Friday that the country’s uranium enrichment program serves as a deterrent against foreign threats and is essential for peaceful purposes, including medical use.

“Enrichment is a critical factor in preventing foreign powers from launching attacks on Iran,” said Ebrahim Rezaei, a member of the parliament’s national security and foreign policy committee, according to state media. “It has helped stop enemies from striking our country.”

He said Iran enriches uranium for non-military purposes, such as fueling the Tehran research reactor, which produces medicine for cancer patients.

Rezaei warned that surrendering enrichment would only lead to further pressure from the West. “If we give up this capability, they will next target our defense power,” he said.

US-Iran talks appear unlikely to lead to an agreement, with the United States insisting that Tehran dismantle its uranium enrichment program, CNN cited two Iranian sources as saying.

Iran’s participation in the fifth round of talks in Rome on Friday is solely to gauge Washington’s latest stance rather than pursue a potential breakthrough, the sources added.

“The media statements and negotiating behavior of the United States has widely disappointed policy-making circles in Tehran,” CNN quoted the two Iranian sources as saying in a joint message.

“From the perspective of decision-makers in Tehran, when the US knows that accepting zero enrichment in Iran is impossible and yet insists on it, it is a sign that the US is fundamentally not seeking an agreement and is using the negotiations as a tool to intensify pressure.”

They added that while some Iranian officials initially hoped for a “win-win” compromise, a consensus has since formed that the Trump administration is pushing the talks toward deadlock. With the current US position, the sources said, the negotiations are becoming unproductive and may not continue much longer.

The sources said Tehran no longer takes seriously US efforts to distance itself from Israel’s position and believes the American proposals follow the agenda of Israeli Prime Minister Benjamin Netanyahu, who has demanded that Iran be barred from all uranium enrichment.

They suggested that Tehran will likely take a tougher stance unless the US offers tangible concessions.