“Those who say, ‘Why don’t you negotiate directly with the United States and solve the issues,’ are superficial; because the reality is different," Khamenei said during a meeting with his supporters in Tehran.
"Given America’s true objective in its hostility toward Iran, these issues are unsolvable."
“The enemies, after facing the steadfast unity of the nation, officials, and armed forces, and after suffering heavy defeats in military attacks, have realized that Iran and the Islamic system cannot be subdued by war or forced into obedience," he said.
Khamenei added that enemies had underestimated Iran’s resilience and wrongly believed attacks would separate the people from the state.
The 86-year-old ruler's remarks came one week after Iran's Reform Front issued a controversial statement urging direct negotiations with Washington, suspension of uranium enrichment, and acceptance of full IAEA monitoring in exchange for sanctions relief.