"If the main issue is ensuring that Iran does not pursue nuclear weapons, this is achievable and not a difficult matter," Araghchi said.
Trump said on Tuesday he hoped for an agreement denying Iran nuclear weapons.
"They cannot have a nuclear weapon," he told reporters at a press conference held after signing a memorandum to restore his so-called maximum pressure policy against Iran.
"If ... they can convince us that they won't, and I hope they can," Trump continued, "It's actually very easy to do, I think they're going to have an unbelievable future."
The US President's directive on squeezing Tehran on Tuesday seeks to deny Iran nuclear weapons, limit its ballistic missile program and halt support for terrorism.
The head of Iran's Atomic Energy Organization, Mohammad Eslami, also weighed in on Trump's directive, saying Tehran has not and will never pursue nuclear weapons.