Ali Bagheri-Kani's remarks come as he prepares to address the United Nations Security Council in New York on issues not directly related to Iran.
The United States under President Donald Trump withdrew from in 2018 from the nuclear accord between Iran and six world powers which restricted Tehran's nuclear program.
Indirect talks between the US and Tehran to revive the deal during the Biden administration have stalled. Iran is still part of the agreement but it has decreased its commitments due to US sanctions imposed on it.
Newsweek said: "On the foreign policy front, he (Bagheri Kani) said that Tehran remained open to resuming negotiations with Washington toward restoring mutual participation in a nuclear deal."
However, Iran also intended to foster its deepening ties with China, Russia and neighboring nations, it quoted him as saying. Iran will also call for greater action against Israel in view of the Gaza war, he said.
The Biden administration said last week the United States was not ready to resume nuclear talks with Iran under its new president. With the election of Masoud Pezeshkian earlier in July, some speculated that Tehran intended to hold more serious talks with Washington, but so far the new president has signaled the continuation of Iran's regional policies of projecting power.