The EU foreign policy chief Josep Borrell, speaking at a joint news conference with his Saudi Arabian counterpart, said he hoped nuclear talks between global powers and Iran would restart in Vienna "soon".
The EU diplomat, who is in Riyadh following visits to Qatar and the United Arab Emirates, said he briefed his partners on the prospects for restarting nuclear talks and exchanged views with Saudi officials on Yemen and Afghanistan.
Turning to the region, he said the EU was ready to pursue trade deals with Gulf countries, saying the bloc supported Saudi Arabia's modernization drive.
Brussels was also engaging on human rights and voiced hope the dialogue would produce "real results", he added.
Saudi Arabia's social and economic reform drive has been accompanied by a crackdown on dissent, which drew intense international scrutiny following the 2018 murder of Saudi journalist Jamal Khashoggi at the kingdom's Istanbul consulate.
Riyadh has also faced criticism over Yemen, where it leads a military coalition that has been battling the Iran-aligned Houthi movement for over six years.
Describing Yemen as a "terrible tragedy", Borrell voiced support for a peaceful settlement of the conflict, largely seen in the region as a proxy war between Saudi Arabia and Iran.
Saudi Foreign Minister Prince Faisal bin Farhan al-Saud said Riyadh has a "very robust" dialogue with the United States to end the war.