US officials believe Israel eyeing possible Iran regime change - CNN

"Absolutely, 100%. I support them completely. They have the right to defend themselves," Oklahoma Republican Markwayne Mullin told Iran International.

"People said, 'Well, Iran didn’t attack them.' Well, actually, Iran has been attacking them for many years through their sponsorship of terror—through Hamas, through the Houthis, and through Hezbollah."

Asked if he backed regime change in Iran, Senator Mullin demurred.

"That’s not up to us. That is up to the Iranian people. That’s a decision they have to make. What we’re trying to do is make sure they never get a nuclear weapon. As far as regime change goes, let the Iranians pick that fight."

The Israeli military's head of operations Major General Oded Basiuk on Friday praised intelligence gathering on Iran's "nuclear program, the scientists, the sites, and the military leadership."

Iran was due to respond, he added, and defending the home front and military was key.

"One of the most important things now is the civilian and military home front, because the enemy’s response will come, and we must minimize the damage, maintain functional continuity, and preserve our offensive capabilities.”

Israel's attack on Iran was eight months in the making and US President Donald Trump opposed the campaign in public while backing it in private, Axios reported citing two Israeli officials.

"We had a clear U.S. green light," Axios quoted one of the officials as saying.

Axios reported Israel's military assessed Iran could race to a nuclear bomb more quickly than previously thought if it so chose and that an underground uranium enrichment facility impervious even to US bombers was due to come online in weeks.

Citing Israeli officials, Axios reported that Trump and Israeli Prime Minister Benjamin Netanyahu coordinated the strike plans in a phone call on Monday.

A new round of Israeli attacks is targeting various parts of Tehran and Qom, according to Iranian media reports and messages sent to Iran International.

Garmdareh and Karaj in western Tehran and areas in southern Tehran have been the new targets.

Iranian military command decimated

At least 20 top Iranian figures were killed, including:

• IRGC chief Hossein Salami
• Chief of Staff Mohammad Bagheri
• Aerospace Force Commander Amir Ali Hajizadeh
• Top nuclear scientists and advisors

Supreme Leader Khamenei made immediate appointments:

• Mohammad Pakpour (IRGC)
• Abdolrahim Mousavi (Armed Forces)
• Ahmad Vahidi (Revolutionary Guards)

Trump backs strikes, says ‘more brutal’ planned

US President Trump praised the Israeli operation, warning Tehran to negotiate before “it’s too late”:

• Revealed Iran had ignored a 60-day ultimatum
• Claimed Iranian hardliners “are all dead now”
• US Navy destroyers have been repositioned in the Mediterranean
• Former envoy Brett McGurk called fears of regional war “overheated”

Civilian toll and domestic fallout

Unofficial Iranian reports say 78 killed, 329 injured in Tehran province.

• Protests erupted across Iran
• Emergency teams deployed to over 60 locations
• Internet restrictions imposed; all flights suspended
• Cultural sites closed and artifacts moved to secure storage

Damage to nuclear and military sites

• Israel claimed “significant damage” to the Natanz facility
• Dozens of missile, radar, and drone sites destroyed
• Mossad reportedly disrupted hundreds of missile launches
• Iran said Fordow was unharmed; Natanz suffered only surface-level damage
• IAEA confirmed no radiation leaks and is assessing damage

Iran vows to strike back

Iran says it will respond “decisively and proportionately”:

• President Pezeshkian promised a “regret-inducing” response
• IRGC vowed preplanned retaliation
• FM Araghchi invoked Article 51 of the UN Charter
• Iran summoned the Swiss envoy (representing US interests), warning against any US military support to Israel
• Iran warned the US must be held “accountable for enabling the attacks”
• Iranian lawmakers urged Khamenei to authorize nuclear weapons

Regional and international reactions

• UN Security Council and IAEA Board to meet urgently
• EU voiced grave concern, warning of a spiral of violence
• Russia, China, Turkey, Saudi Arabia, and Italy condemned or urged restraint
• EU reaffirmed diplomatic efforts to prevent Iran from acquiring nuclear weapons
• Hamas praised Iran’s role; Hezbollah condemned the attack but will not retaliate

Diplomatic flurry

• Netanyahu has spoken or will speak with leaders of the US, Russia, Britain, France, Germany and India
• Iran's Araghchi demanded IAEA condemnation
• Iranian ambassador summoned to Germany’s foreign ministry
• Italy’s FM Tajani spoke with Araghchi, urging de-escalation and diplomacy

Market and aviation Disruption

• Oil prices surged 12%, surpassing $77/barrel
• Wall Street opened lower as investors fled risk
• Iran, Iraq, Jordan, and Israel closed airspace; over 1,800 flights disrupted
• Major carriers suspended operations; shipping advisories issued in Hormuz and Red Sea

Israeli emergency measures

• Israel declared a national emergency
• All embassies worldwide closed; citizens told to avoid public identification
• Senior leadership relocated amid threats of retaliation